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In order to discover the influence rules of paperbased passive micromixer’s parameters on mixing effect of pesticides, the Yshaped micromixer, Zshaped micromixer, squarewave micromixer were selected and the relationships among the parameters of each kind micromixer and mixing performance by experiments were researched. Then optimal parameters of each kind micromixer were chosen, and mixing performances of three micromixers were contrasted under the optimal parameters. The results of experiments show that Yshaped micromixer’s optimal parameters are inlet velocity of 0.010mL/min, inlet angle of 30°, Zshaped micromixer’s optimal parameters are inlet velocity of 0.010mL/min, peak separation of 3mm, corner angle of 30°, squarewave micromixer’s optimal parameters are inlet velocity of 0.010mL/min, wave height of 2mm, wave width of 5mm, and under their optimal parameters, Yshaped micromixer’s outlet mixing intensity is 0.6227, Zshaped micromixer’s outlet mixing intensity is 0.6902, squarewave micromixer’s outlet mixing intensity is 0.7326. The squarewave micromixer has the best mixing performance. Paperbased passive micromixer has some fibers in its channel, it can provide dynamic of flowing and enhance the diffusion of liquid pesticides. On the other hand, it can limit the convection to a certain degree. This article researched the mixing performance of paperbased passive micromixer for the first time internationally.