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Focusing on the problem of low drug utilization caused by uneven drug distribution when adding granular drugs to pig feed, a precise feed and drug integrated feeder was designed, with a metering inclined flute-wheel as the discharge device, and key components were designed to achieve real-time and accurate dosing under a given mass ratio range. Using the discrete element analysis software EDEM 2018 for discharge stability analysis, it was found that the stability of the feed discharge flute-wheel was good when the speed was 40~60r/min. Based on the (100~250)∶1 material and drug mass ratio, the drug discharge flute-wheel speed was determined to be 10~20r/min. The force chain analysis showed that the external force acting on feed particles and drug particles during the operation of the flute-wheel discharge device were smaller than the crushing force, and it would not cause particle breakage during the entire movement process. Through prototype testing, it was found that within the given speed range, the achievable material and drug mass ratio range was (93.4~251.8)∶1, and the given material and drug mass ratio was within this range. A bench test was conducted on the feed and drug ratio, and the experimental results showed that the precise feed and drug integrated feeder can achieve real-time and precise dosing into the feed, solving the problem of uneven distribution of small particle size and small flow rate drug particles in large particle size and large flow rate feed particles.